Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784953 | 0.88 | MAOA (0.51) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9306855 | 0.88 | KDM4E (0.51) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL9155007 | 0.87 | NQO1 (0.46) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL9308703 | 0.85 | POLB (0.45) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL8784359 | 0.85 | KDM4E (0.64) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL9137916 | 0.81 | KDM4E (0.41) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL9137558 | 0.81 | ALDH1A1 (0.41) | KDM4EMAPTALDH1A1HPGDKMT2A | |
| SCHEMBL11330155 | 0.78 | KDM4E (0.56) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL9153220 | 0.73 | ALOX5 (0.58) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL8786260 | 0.73 | MAOB (0.54) | KDM4EMAPTALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278186-A | Substituted with secondary amide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-11 | — | — | US | disclosed |