Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638150 | 0.89 | AGTR1 (0.45) | ABCG2AGTR1KCNJ1POLBSMN1; SMN2 | |
| SCHEMBL7348668 | 0.88 | POLB (0.40) | ABCG2AGTR1KCNJ1POLBSMN1; SMN2 | |
| SCHEMBL30743612 | 0.82 | ABCG2 (0.55) | ABCG2AGTR1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL2161550 | 0.81 | ABCG2 (0.41) | ABCG2AGTR1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9033772 | 0.78 | AGTR1 (0.41) | ABCG2AGTR1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7749400 | 0.78 | AGTR1 (0.42) | ABCG2AGTR1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7352872 | 0.77 | ABCG2 (0.41) | ABCG2AGTR1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4638378 | 0.76 | SMN1; SMN2 (0.51) | POLBSMN1; SMN2ALDH1A1NPC1HPGD | |
| SCHEMBL27315990 | 0.76 | AGTR1 (0.43) | ABCG2AGTR1POLBSMN1; SMN2NPC1 | |
| SCHEMBL15391225 | 0.74 | AGTR1 (0.47) | ABCG2AGTR1POLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070491-C | Process for the preparation of 1-butyl-2- [ 2' - (2H-tetrazol-5-yl) -biphenyl-4-ylmethyl ] -1H-indole-3-carboxylic acid | SYNTEX INC (US) | 2001-09-05 | — | — | CN | disclosed |
| CN-1070193-C | Process for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid | SYNTEX INC (US) | 2001-08-29 | — | — | CN | disclosed |
| CN-1149294-A | Process for the preparation of 1-butyl-2- [2- (2H-tetrazol-5-yl) -biphenyl-4-ylmethyl) -1H-indole-3-carboxylic acid | SYNTEX INC (US) | 1997-05-07 | — | — | CN | disclosed |
| EP-0760815-A1 | PROCESSES FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032962-A1 | PROCESSES FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-12-07 | — | — | WO | disclosed |