Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18160225 | 0.99 | TSPO (0.36) | TSPOALDH1A1PDK2DNM1KDM4E | |
| SCHEMBL16810702 | 0.99 | TSPO (0.36) | TSPOALDH1A1PDK2DNM1KDM4E | |
| SCHEMBL18457743 | 0.99 | TSPO (0.36) | TSPOALDH1A1PDK2DNM1KDM4E | |
| SCHEMBL16810747 | 0.98 | TSPO (0.35) | TSPOALDH1A1PDK2DNM1KDM4E | |
| SCHEMBL25843929 | 0.96 | TSPO (0.34) | TSPOALDH1A1PDK2DNM1 | |
| SCHEMBL20232306 | 0.95 | PDK2 (0.35) | TSPOPDK2PDE6D | |
| SCHEMBL21138936 | 0.95 | ALDH1A1 (0.33) | TSPOALDH1A1KDM4EATML3MBTL1 | |
| SCHEMBL21138925 | 0.95 | PDK2 (0.36) | TSPOPDK2PDE6D | |
| SCHEMBL15213618 | 0.95 | PDK2 (0.36) | TSPOPDK2PDE6D | |
| SCHEMBL18457468 | 0.94 | L3MBTL1 (0.40) | TSPOALDH1A1PDK2KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859111-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| US-8859111-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| US-20120126179-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120126179-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120126179-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EPB41, HCN4, EPB41L2 | TSPO 991/4885ALDH1A1 327/4885PDK2 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.