Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.36 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138925 | 1.00 | PDK2 (0.36) | PDK2PDE6DTYMSTSPO | |
| SCHEMBL17816795 | 0.99 | PDK2 (0.35) | PDK2PDE6DTYMSTSPO | |
| SCHEMBL16810745 | 0.99 | PDK2 (0.35) | PDK2PDE6DTYMSTSPO | |
| SCHEMBL20232306 | 0.97 | PDK2 (0.35) | PDK2PDE6DTSPO | |
| SCHEMBL18457743 | 0.96 | TSPO (0.36) | PDK2PDE6DTSPO | |
| SCHEMBL16810747 | 0.95 | TSPO (0.35) | PDK2TSPO | |
| SCHEMBL8784649 | 0.95 | TSPO (0.36) | PDK2PDE6DTSPO | |
| SCHEMBL25843929 | 0.94 | TSPO (0.34) | PDK2TSPO | |
| SCHEMBL16810702 | 0.94 | TSPO (0.36) | PDK2PDE6DTSPO | |
| SCHEMBL18160225 | 0.94 | TSPO (0.36) | PDK2PDE6DTSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023117836-A1 | ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | WO | disclosed |
| US-11387414-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-07-12 | — | — | US | disclosed |
| US-10944056-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-03-09 | — | — | US | disclosed |
| US-20200235305-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-23 | — | — | US | disclosed |
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| EP-3101088-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-29 | — | — | EP | disclosed |
| US-9812648-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9812648-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| EP-3235892-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2017-10-25 | — | — | EP | disclosed |
| EP-3101088-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2016-12-07 | — | — | EP | disclosed |
| EP-2814906-B1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-10-19 | — | — | EP | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| WO-2013120577-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | PDK2 1024/4885PDE6D 1972/4885TYMS 1372/4885 |
| US-11387414-B2 | Spirobifluorene compounds for organic electroluminescent devices | PKD1, PIEZO1, AQP1 | PDK2 233/4885PDE6D 1573/4885TYMS 2472/4885 |
| US-20200235305-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PKD1, PIEZO1, AQP1 | PDK2 283/4885PDE6D 1390/4885TYMS 2496/4885 |
| US-10944056-B2 | Materials for organic electroluminescent devices | PIEZO1, TMEM109, EPN1 | PDK2 448/4885PDE6D 1786/4885TYMS 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.