Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785737 | 0.86 | SMN1; SMN2 (0.37) | ALDH1A1KDM4EGAATSHRCARM1 | |
| SCHEMBL8785157 | 0.80 | FAAH (0.38) | KDM4EGAAKMT2ASMN1; SMN2 | |
| SCHEMBL8786684 | 0.79 | CYP1A2 (0.39) | ALDH1A1KDM4ECARM1SMN1; SMN2 | |
| SCHEMBL8786169 | 0.78 | LMNA (0.40) | KMT2ASMN1; SMN2 | |
| SCHEMBL8785926 | 0.78 | KMT2A (0.40) | ALDH1A1GAATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL8786282 | 0.77 | CARM1 (0.33) | CARM1 | |
| SCHEMBL8789020 | 0.76 | CARM1 (0.44) | ALDH1A1GAAHSD17B10CARM1KMT2A | |
| SCHEMBL8785043 | 0.76 | NPBWR1 (0.41) | ALDH1A1KDM4EGAACARM1KMT2A | |
| SCHEMBL8373693 | 0.76 | ALDH1A1 (0.46) | TAS1R3TAS1R1ALDH1A1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL8786807 | 0.75 | CARM1 (0.43) | ALDH1A1GAAHSD17B10CARM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650961-B1 | Substituted heterocyclic carboxylic acid amides, their preparation, and their use as medicaments | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0650961-A1 | Substituted heterocyclic carboxylic acid amides, their preparation, and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-03 | — | — | EP | disclosed |