Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.65 |
| ▸ | HTR2C | P28335 | 4/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863914 | 0.94 | HTR1A (0.62) | HTR1AHTR2CDRD2 | |
| SCHEMBL8785263 | 0.93 | HTR1A (0.63) | HTR1AHTR2CDRD2 | |
| SCHEMBL8785451 | 0.88 | HTR1A (0.66) | HTR1AHTR2CDRD2 | |
| SCHEMBL9658518 | 0.85 | HTR1A (0.68) | HTR1AHTR2CDRD2 | |
| SCHEMBL8785358 | 0.82 | HTR1A (0.73) | HTR1AHTR2CDRD2 | |
| SCHEMBL10835764 | 0.81 | DRD2 (0.68) | HTR1AHTR2CDRD2 | |
| SCHEMBL10865110 | 0.81 | HTR1A (0.75) | HTR1AHTR2CDRD2 | |
| SCHEMBL9449665 | 0.81 | MAOB (0.48) | HTR1AHTR2CDRD2 | |
| SCHEMBL10863889 | 0.81 | DRD4 (0.65) | HTR1ADRD2 | |
| SCHEMBL10864715 | 0.80 | HTR1A (0.59) | HTR1AHTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478446-B1 | Heterocyclic alkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-11-19 | — | — | EP | disclosed |
| EP-0478446-A1 | Heterocyclic alkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-04-01 | — | — | EP | disclosed |