Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449443 | 0.95 | SIGMAR1 (0.53) | MAOBMAOASIGMAR1EPHX2HTR1A | |
| SCHEMBL8785948 | 0.82 | HTR1A (0.56) | SIGMAR1HTR1ADRD2HTR2ADRD4 | |
| SCHEMBL8787203 | 0.81 | HTR1A (0.65) | HTR1ADRD2HTR2C | |
| SCHEMBL9659923 | 0.78 | HTR1A (0.65) | SIGMAR1HTR1ADRD2HTR2AHTR2C | |
| SCHEMBL8787679 | 0.78 | DRD2 (0.53) | SIGMAR1HTR1ADRD2HTR2ADRD4 | |
| SCHEMBL10863549 | 0.77 | DRD2 (0.56) | MAOBMAOASIGMAR1HTR1ADRD2 | |
| SCHEMBL8789687 | 0.76 | MAOB (0.42) | MAOBMAOAEPHX2 | |
| SCHEMBL13266979 | 0.76 | EPHX2 (0.63) | MAOBMAOAEPHX2 | |
| SCHEMBL10863914 | 0.74 | HTR1A (0.62) | HTR1ADRD2HTR2ADRD4HTR2C | |
| SCHEMBL8785694 | 0.74 | MAOB (0.55) | MAOBMAOAEPHX2HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234924-A | Hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-08-10 | — | — | US | claimed |