Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.51 |
| ▸ | CYCS | P99999 | 4/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 5/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476593 | 0.91 | TOP1 (0.59) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL29477148 | 0.91 | TOP1 (0.59) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL3290035 | 0.90 | TERT (0.53) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL30022815 | 0.88 | TOP1 (0.57) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL28629714 | 0.88 | TOP1 (0.57) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL29141456 | 0.88 | TOP1 (0.57) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL21257046 | 0.84 | TOP1 (0.56) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL79276 | 0.84 | TOP1 (0.47) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL21734341 | 0.82 | TOP1 (0.62) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL768992 | 0.82 | TERT (0.57) | TOP1CYCSABCG2ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120126214-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | UNITED STATES DEPARTMENT OF ENERGY | 2012-05-24 | — | — | US | disclosed |
| US-8129520-B2 | Methods and intermediates for the synthesis of dipyrrin-substituted porphyrinic macrocycles | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110197969-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | UNITED STATES DEPARTMENT OF ENERGY | 2011-08-18 | — | — | US | disclosed |
| US-7947828-B2 | Methods and intermediates for the synthesis of dipyrrin-substituted porphyrinic macrocycles | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-05-24 | — | — | US | disclosed |
| US-20100200066-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | UNITED STATE DEPARTMENT OF ENERGY | 2010-08-12 | — | — | US | disclosed |
| US-7723513-B2 | for production of molecular memory devices, solar cells and light harvesting arrays | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-05-25 | — | — | US | disclosed |
| US-7332599-B2 | Reacting a dipyrromethane with an oxidant and a metal salt to produce the bis(dipyrrinato)metal complex; for making molecular memory devices, solar cells and light harvesting arrays | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-02-19 | — | — | US | disclosed |
| US-20070191600-A1 | for production of molecular memory devices, solar cells and light harvesting arrays | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100200066-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | HCCS, PPOX, DHPS | TOP1 289/4885CYCS 1826/4885ABCG2 4424/4885 |
| US-20120126214-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | HCCS, PPOX, DHPS | TOP1 289/4885CYCS 1826/4885ABCG2 4424/4885 |
| US-20110197969-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES | HCCS, PPOX, DHPS | TOP1 289/4885CYCS 1826/4885ABCG2 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.