Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705489 | 0.89 | CYP3A4 (0.50) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL8787882 | 0.85 | ALDH1A1 (0.49) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL8759316 | 0.85 | CYP3A4 (0.49) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL1459781 | 0.85 | TSHR (0.56) | ALDH1A1TSHRMAPTRAB9AKMT2A | |
| SCHEMBL8787638 | 0.85 | ALDH1A1 (0.50) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL8787936 | 0.85 | MAPT (0.55) | CYP3A4ALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL8788640 | 0.84 | AR (0.44) | CYP3A4ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL5108863 | 0.84 | HCAR3 (0.48) | CYP3A4ALDH1A1TSHRMAPTRAB9A | |
| SCHEMBL8787027 | 0.84 | CYP3A4 (0.48) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL753770 | 0.83 | KMT2A (0.45) | CYP3A4ALDH1A1TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508682-B1 | Antibiotic carbapenem derivatives | ZENECA LTD (GB) | 1997-07-23 | — | — | EP | disclosed |
| CN-1066657-A | Antimicrobial compounds | ICI PLC (GB) | 1992-12-02 | — | — | CN | disclosed |
| WO-1992017481-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD. (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0508682-A1 | Antibiotic carbapenem derivatives | ZENECA LIMITED (GB) | 1992-10-14 | — | — | EP | disclosed |