Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787548 | 0.82 | MCHR1 (0.34) | MCHR1ROCK2HDAC8HDAC6NTMT1 | |
| SCHEMBL8788450 | 0.78 | GPR119 (0.43) | MCHR1ROCK2HDAC8HDAC6MMP1 | |
| SCHEMBL28830319 | 0.77 | CYP1A2 (0.39) | LMNAMCHR1 | |
| SCHEMBL8787403 | 0.76 | CYP2D6 (0.36) | LMNAMCHR1NPC1NTMT1 | |
| SCHEMBL8103747 | 0.76 | MCHR1 (0.48) | LMNAMCHR1NPC1 | |
| SCHEMBL28887345 | 0.74 | ROCK2 (0.45) | ROCK2HDAC8HDAC6NPC1NTMT1 | |
| SCHEMBL8090512 | 0.74 | LMNA (0.38) | LMNAMCHR1 | |
| SCHEMBL8661026 | 0.72 | CNR1 (0.45) | MCHR1CYP17A1CCNE1CDK2 | |
| SCHEMBL28377659 | 0.72 | MCHR1 (0.34) | MCHR1ROCK2 | |
| SCHEMBL28382325 | 0.72 | MCHR1 (0.34) | MCHR1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |