SCHEMBL8788307

SCHEMBL8788307

NS(=O)(=O)c1cnc2ccccc2c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.69
CA1 P00915 2/20 0.69
CA2 P00918 2/20 0.69
CA9 Q16790 2/20 0.69
CYP1A2 P05177 2/20 0.57
LMNA P02545 2/20 0.53
ALDH1A1 P00352 3/20 0.50
ALPL P05186 3/20 0.50
KDM4E B2RXH2 1/20 0.50
SLC40A1 Q9NP59 1/20 0.50
MGAM O43451 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
CNR2 P34972 1/20 0.45
BCAT1 P54687 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
KDR P35968 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29927370 1.00 CA12 (0.69) CA12CA1CA2CA9CYP1A2
SCHEMBL28304469 0.98 CA12 (0.67) CA12CA1CA2CA9CYP1A2
SCHEMBL26613580 0.82 CA2 (1.00) CA12CA1CA2CA9CYP1A2
SCHEMBL1771001 0.81 CA12 (0.51) CA12CA1CA2CA9CYP1A2
SCHEMBL2377240 0.81 CA12 (0.51) CA12CA1CA2CA9CYP1A2
SCHEMBL2377244 0.81 ALDH1A1 (0.54) CA12CA1CA2CA9CYP1A2
SCHEMBL10296114 0.81 MGAM (0.51) CA12CA1CA2CA9CYP1A2
SCHEMBL29712704 0.80 ALDH1A1 (0.53) CA12CA1CA2CA9CYP1A2
SCHEMBL4668553 0.80 ALDH1A1 (0.53) CA12CA1CA2CA9CYP1A2
Hydrochloric Acid SCHEMBL27809967 0.80 MGAM (0.50) CA12CA1CA2CA9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115397972-A In vitro poultry food 优良肉品公司 2022-11-25 CN claimed
EP-3983529-A1 IN VITRO AVIAN FOOD PRODUCT Good Meat, Inc. (US) 2022-04-20 EP claimed
CN-108884046-B Chemical compounds as inhibitors of kinase activity 葛兰素史克知识产权开发有限公司 2021-11-09 CN claimed
US-20200392461-A1 IN VITRO AVIAN FOOD PRODUCT AHIMSA FOUNDATION 2020-12-17 US claimed
WO-2020252388-A1 IN VITRO AVIAN FOOD PRODUCT JUST, INC. (US) 2020-12-17 WO claimed
CN-110121499-A (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides 优时比制药有限公司 2019-08-13 CN claimed
CN-103384662-A Novel 1, 2-bis-sulfonamide derivatives as chemokine receptor modulators ALLERGAN INC 2013-11-06 CN claimed
EP-0757674-A1 SUBSTITUTED SULFONAMIDES AS SELECTIVE $g(b) 3? AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY Merck & Co., Inc. (US) 1997-02-12 EP claimed
WO-1995029159-A1 SUBSTITUTED SULFONAMIDES AS SELECTIVE β3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY MERCK & CO., INC. (US) 1995-11-02 WO claimed
US-20260055157-A1 METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS NOVARTIS AG (CH) 2026-02-26 US disclosed
CN-118045081-B Application of settop alcohol in preparing antitumor drug 中山大学孙逸仙纪念医院 2025-04-08 CN disclosed
CN-116478129-B Quinoline compound and use thereof 深圳默元生物科技有限公司 2025-01-07 CN disclosed
US-20240400502-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME UNIV QUEENSLAND (AU) 2024-12-05 US disclosed
CN-113582889-B Sulfonylureas and related compounds and uses thereof 昆士兰大学 2024-09-20 CN disclosed
CN-107428696-A Sulfonylureas and related compounds and uses thereof 昆士兰大学 2017-12-01 CN disclosed
WO-2017184604-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY IFM THERAPEUTICS, INC (US) 2017-10-26 WO disclosed
WO-2017095751-A1 COMPOSITIONS AND METHODS FOR MODULATING CANCER CELL METABOLISM PARTIKULA LLC (US) 2017-06-08 WO disclosed
US-20170042930-A1 METHOD OF TREATING A DISEASE USING A GLYCOLYTIC DEPENDENT COMPOUND ETHICON, INC. 2017-02-16 US disclosed
WO-2016131098-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME THE UNIVERSITY OF QUEENSLAND (AU) 2016-08-25 WO disclosed
CN-103384662-A Novel 1, 2-bis-sulfonamide derivatives as chemokine receptor modulators ALLERGAN INC 2013-11-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400502-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, PYCARD, IAPP CA12 4653/4885CA1 4141/4885CA2 2434/4885
US-20260055157-A1 METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS IL2RA, IL2, ICOS CA12 314/4885CA1 1377/4885CA2 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.