Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787181 | 0.90 | FFAR4 (0.49) | NOTUMFFAR4DRD2DRD3KCNH2 | |
| SCHEMBL8788513 | 0.83 | CHRM4 (0.41) | NOTUMFFAR4DRD2DRD3KCNH2 | |
| SCHEMBL8788328 | 0.80 | NOTUM (0.38) | NOTUMFFAR4DRD2DRD3KCNH2 | |
| SCHEMBL8093681 | 0.80 | NOTUM (0.45) | NOTUMFFAR4DRD2DRD3KCNH2 | |
| SCHEMBL8556361 | 0.80 | DRD2 (0.44) | NOTUMFFAR4DRD2DRD3KCNH2 | |
| SCHEMBL8556168 | 0.77 | DRD2 (0.44) | NOTUMFFAR4DRD2DRD3KCNH2 | |
| SCHEMBL8786870 | 0.76 | NOTUM (0.43) | NOTUMFFAR4DRD2DRD3KCNH2 | |
| SCHEMBL8791460 | 0.76 | AR (0.43) | NOTUM | |
| SCHEMBL6507723 | 0.74 | DRD2 (0.42) | NOTUMDRD2DRD3KCNH2MCHR1 | |
| SCHEMBL8554346 | 0.74 | MCHR1 (0.40) | NOTUMFFAR4DRD2DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |