Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735222 | 0.94 | TSHR (0.52) | MAPTALDH1A1TSHRNPC1HPGD | |
| SCHEMBL7724894 | 0.83 | KCNJ5 (0.51) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7724422 | 0.83 | MAPT (0.62) | MAPTALDH1A1TSHRNPC1HPGD | |
| SCHEMBL20037048 | 0.75 | POLB (0.59) | MAPTALDH1A1TSHRNPC1HPGD | |
| SCHEMBL10745183 | 0.72 | POLB (0.55) | MAPTALDH1A1TSHRHPGDPOLB | |
| SCHEMBL30428722 | 0.71 | BRD4 (0.61) | MAPTALDH1A1TSHRNPC1HPGD | |
| SCHEMBL10631908 | 0.71 | BRD4 (0.61) | MAPTALDH1A1TSHRNPC1HPGD | |
| SCHEMBL7736629 | 0.71 | MEN1 (0.70) | HPGDL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL20037239 | 0.70 | L3MBTL1 (0.51) | MAPTALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL20037200 | 0.70 | L3MBTL1 (0.48) | MAPTALDH1A1TSHRL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |