Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.42 |
| ▸ | MAOA | P21397 | 9/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449665 | 0.76 | MAOB (0.48) | MAOBMAOAEPHX2 | |
| SCHEMBL9449443 | 0.76 | SIGMAR1 (0.53) | MAOBMAOAEPHX2LMNASMN1; SMN2 | |
| SCHEMBL15586614 | 0.67 | EPHX2 (0.63) | MAOBMAOAEPHX2LMNA | |
| SCHEMBL10767158 | 0.64 | IDH1 (0.50) | LMNA | |
| SCHEMBL17387582 | 0.63 | DRD3 (0.37) | LMNA | |
| SCHEMBL279937 | 0.60 | EPHX2 (1.00) | MAOBMAOAEPHX2LMNA | |
| SCHEMBL14565134 | 0.60 | MAOB (0.55) | MAOBMAOAEPHX2LMNA | |
| SCHEMBL16227246 | 0.59 | ACHE (0.68) | — | |
| SCHEMBL13261424 | 0.59 | GNAI3 (0.53) | MAOBLMNA | |
| Propene SCHEMBL28191652 | 0.59 | GNAI3 (0.57) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478446-B1 | Heterocyclic alkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-11-19 | — | — | EP | claimed |
| EP-0478446-A1 | Heterocyclic alkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-04-01 | — | — | EP | claimed |