Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357679 | 0.85 | GLA (0.40) | HTR2CSMN1; SMN2CYP2C19NPC1RAB9A | |
| SCHEMBL8790782 | 0.79 | CHRM1 (0.47) | ACE2PREPHTR2CSLC15A1SMN1; SMN2 | |
| SCHEMBL23838521 | 0.78 | HTR2C (0.42) | HTR2CSMN1; SMN2NPC1RAB9AHRH3 | |
| SCHEMBL7363294 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL7363296 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL10853040 | 0.75 | ALDH1A1 (0.49) | HTR2CSMN1; SMN2CYP2C19NPC1RAB9A | |
| SCHEMBL22193270 | 0.74 | LTA4H (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL26327917 | 0.72 | HRH3 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AHRH3 | |
| SCHEMBL20428478 | 0.70 | TSHR (0.48) | HTR2CSMN1; SMN2CYP2C19NPC1RAB9A | |
| SCHEMBL4143101 | 0.70 | ALDH1A1 (0.59) | SMN1; SMN2CYP2C19NPC1RAB9AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |