Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953776 | 0.82 | KMT2A (0.47) | ALDH1A1MGLL | |
| SCHEMBL7070229 | 0.79 | KMT2A (0.47) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL29426173 | 0.78 | SLC6A2 (0.49) | — | |
| SCHEMBL21939075 | 0.78 | MGLL (0.43) | MGLL | |
| SCHEMBL8189491 | 0.77 | KMT2A (0.42) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8790743 | 0.77 | PKM (0.55) | ALDH1A1MGLLTSHR | |
| SCHEMBL16138331 | 0.75 | MGLL (0.49) | MGLL | |
| SCHEMBL16138311 | 0.75 | MGLL (0.49) | MGLL | |
| SCHEMBL16138316 | 0.75 | MGLL (0.49) | MGLL | |
| SCHEMBL25308270 | 0.75 | PDK1 (0.46) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785933-A1 | INDOLE DERIVATIVES AS 5HT1-LIKE AGONISTS | Pfizer Limited (GB) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011195-A1 | INDOLE DERIVATIVES AS 5HT1-LIKE AGONISTS | PFIZER LIMITED (GB) | 1996-04-18 | — | — | WO | disclosed |