SCHEMBL2953776

SCHEMBL2953776

O=S(=O)(Cc1ccccc1)OCC1CO1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
PRMT5 O14744 1/20 0.46
WDR77 Q9BQA1 1/20 0.46
MGLL Q99685 3/20 0.46
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
FAAH O00519 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
ELANE P08246 1/20 0.40
PRTN3 P24158 1/20 0.40
PRSS3 P35030 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28582521 0.84 TDP1 (0.45) KMT2ATDP1PRMT5WDR77MGLL
SCHEMBL8790740 0.82 ALDH1A1 (0.48) MGLLALDH1A1
SCHEMBL29426173 0.80 SLC6A2 (0.49) KMT2A
SCHEMBL3691428 0.80 CA2 (0.56) KMT2APRMT5WDR77ALDH1A1PKM
SCHEMBL58865 0.77 PRMT5 (0.60) TDP1PRMT5WDR77MGLLALDH1A1
SCHEMBL9844160 0.77 PRMT5 (0.60) TDP1PRMT5WDR77MGLLALDH1A1
SCHEMBL16223323 0.77 KMT2A (0.41) KMT2AALDH1A1FAAHPRSS1PRSS2
SCHEMBL12816499 0.77 KMT2A (0.41) KMT2ALMNAFAAHPRSS1PRSS2
SCHEMBL7067625 0.77 KMT2A (0.47) KMT2AALDH1A1FAAHPRSS1PRSS2
SCHEMBL7070229 0.77 KMT2A (0.47) KMT2AALDH1A1LMNAFAAHPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118715301-A Coating composition for creping paper product manufacture and method for producing the same 索理思科技开曼公司 2024-09-27 CN claimed
CN-118715301-A Coating composition for creping paper product manufacture and method for producing the same 索理思科技开曼公司 2024-09-27 CN disclosed
WO-2023071921-A1 POLYAMIDE COMPOSITE MATERIAL, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海金发科技发展有限公司 2023-05-04 WO disclosed
CN-107250189-A Crosslinking polydiene propylamine copolymer for treating diabetes B 建新公司 2017-10-13 CN disclosed
CN-101365441-B Use of benzo-fused heterocycle sulfamide derivatives for the preparation of a medicament for lowering lipid levels and lowering blood glucose levels JANSSEN PHARMACEUTICA NV 2011-11-16 CN disclosed
US-7763646-B2 Compounds for the treatment of alzheimer's disease ELAN PHARMACEUTICALS, INC. (US) 2010-07-27 US disclosed
CN-101443704-A Positive photosensitive resin composition and porous film obtained therefrom NISSAN CHEMICAL IND LTD (JP) 2009-05-27 CN disclosed
CN-101365441-A Use of benzo-fused heterocycle sulfamide derivatives for lowering lipid levels and lowering blood glucose levels JANSSEN PHARMACEUTICA NV (BE) 2009-02-11 CN disclosed
US-20060128786-A1 Compounds for the treatment of alzheimer's disease ELAN PHARMACEUTICALS, INC. 2006-06-15 US disclosed
EP-1542964-A2 COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE Elan Pharmaceuticals, Inc. (US) 2005-06-22 EP disclosed
EP-0930307-B1 PROCESS FOR THE PREPARATION OF GLYCIDYL ETHERS DAISO CO LTD (JP) 2002-12-04 EP disclosed
EP-0930291-B1 PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXY-1-PROPYL ETHERS DAISO CO LTD (JP) 2002-08-14 EP disclosed
EP-0605729-B1 OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF TAIHO PHARMACEUTICAL CO LTD (JP) 2000-07-26 EP disclosed
US-6087512-A Process for preparation of glycidyl ether DAISO CO., LTD. (JP) 2000-07-11 US disclosed
US-6057476-A Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers DAISO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0930291-A1 PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXY-1-PROPYL ETHERS DAISO CO., LTD. (JP) 1999-07-21 EP disclosed
EP-0930307-A1 PROCESS FOR THE PREPARATION OF GLYCIDYL ETHERS DAISO CO., LTD. (JP) 1999-07-21 EP disclosed
US-5480899-A ANTILIPEMIC AGENTS TAIHO PHARMACEUTICAL CO., LTD. (JP) 1996-01-02 US disclosed
EP-0605729-A1 OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF TAIHO PHARMACEUTICAL CO., LTD. (JP) 1994-07-13 EP disclosed
US-5087773-A Reacting with toluenesulfonic anhydride, contacting with telluride or selenide SYRACUSE UNIVERSITY (US) 1992-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128786-A1 Compounds for the treatment of alzheimer's disease BACE1, BACE2, APP KMT2A 3665/4885TDP1 672/4885PRMT5 1243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.