Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640868 | 0.83 | CHKA (0.50) | CHKAHRH3GRIN2BL3MBTL3L3MBTL1 | |
| SCHEMBL3716319 | 0.81 | L3MBTL1 (0.67) | HRH3GRIN2BL3MBTL3L3MBTL1DRD2 | |
| Hydrochloric Acid SCHEMBL3716101 | 0.80 | L3MBTL1 (0.65) | HRH3GRIN2BL3MBTL3L3MBTL1DRD2 | |
| SCHEMBL3452987 | 0.78 | ADRB2 (0.49) | CHKAHRH3GRIN2BL3MBTL3L3MBTL1 | |
| SCHEMBL18867080 | 0.78 | L3MBTL3 (0.53) | CHKAHRH3GRIN2BL3MBTL3L3MBTL1 | |
| SCHEMBL8618958 | 0.78 | HRH3 (0.51) | CHKAHRH3GRIN2BL3MBTL3L3MBTL1 | |
| SCHEMBL28784973 | 0.78 | HRH3 (0.48) | CHKAHRH3GRIN2BL3MBTL3L3MBTL1 | |
| SCHEMBL28784972 | 0.78 | HRH3 (0.57) | HRH3L3MBTL3L3MBTL1MBTD1KMT2A | |
| SCHEMBL207806 | 0.77 | CHKA (0.67) | CHKAADRB2NCF1PLD1ALDH1A1 | |
| SCHEMBL28112415 | 0.77 | CHKA (0.80) | CHKAADRB2NCF1PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-A1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024586-A1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-08-15 | — | — | WO | disclosed |