Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8477293 | 0.99 | EGFR (0.52) | EGFRLTA4HMCHR1ALOX5FFAR1 | |
| SCHEMBL8482437 | 0.89 | KDM4E (0.48) | EGFRLTA4HMCHR1ALOX5 | |
| Hydrochloric Acid SCHEMBL8477271 | 0.88 | KDM4E (0.47) | EGFRLTA4HMCHR1ALOX5MAOB | |
| SCHEMBL9099717 | 0.86 | LTA4H (0.57) | EGFRLTA4HMCHR1ALOX5 | |
| SCHEMBL8483093 | 0.84 | LMNA (0.50) | LTA4HALOX5FFAR1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL8483603 | 0.83 | LTA4H (0.55) | LTA4HLMNACYP1A2SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL8480079 | 0.81 | RAB9A (0.48) | LTA4HFFAR1LMNACYP1A2PTGS1 | |
| SCHEMBL29985909 | 0.79 | LTA4H (0.62) | EGFRLTA4HMCHR1 | |
| SCHEMBL2477100 | 0.79 | LTA4H (0.75) | EGFRLTA4HMCHR1LMNACYP1A2 | |
| SCHEMBL8581500 | 0.79 | MAOB (0.48) | MCHR1ALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612381-A | 1,2-ethanediol derivative and salt thereof process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-03-18 | — | — | US | claimed |
| EP-0587193-B1 | 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO LTD (JP) | 1997-01-02 | — | — | EP | claimed |
| EP-0587193-A1 | 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-03-16 | — | — | EP | claimed |
| EP-0383281-A1 | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1990-08-22 | — | — | EP | claimed |