Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793354 | 0.90 | OPRM1 (0.55) | OPRM1OPRD1OPRK1SIGMAR1SLC6A4 | |
| SCHEMBL8395140 | 0.88 | OPRM1 (0.57) | OPRM1OPRD1OPRK1CXCR3CHRM2 | |
| SCHEMBL8395142 | 0.88 | OPRM1 (0.57) | OPRM1OPRD1OPRK1CXCR3CHRM2 | |
| SCHEMBL7486456 | 0.88 | OPRM1 (0.60) | OPRM1OPRD1OPRK1SIGMAR1CXCR3 | |
| SCHEMBL7486453 | 0.88 | OPRM1 (0.60) | OPRM1OPRD1OPRK1SIGMAR1CXCR3 | |
| Hydrochloric Acid SCHEMBL7487249 | 0.87 | OPRM1 (0.59) | OPRM1OPRD1OPRK1SIGMAR1CXCR3 | |
| Hydrochloric Acid SCHEMBL7487248 | 0.87 | OPRM1 (0.59) | OPRM1OPRD1OPRK1SIGMAR1CXCR3 | |
| SCHEMBL8396855 | 0.86 | OPRD1 (0.76) | OPRM1OPRD1OPRK1SIGMAR1CXCR3 | |
| SCHEMBL11398571 | 0.86 | OPRD1 (0.76) | OPRM1OPRD1OPRK1SIGMAR1CXCR3 | |
| SCHEMBL8396856 | 0.86 | OPRD1 (0.76) | OPRM1OPRD1OPRK1SIGMAR1CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485636-B1 | INDOLE DERIVATIVE | TORAY INDUSTRIES (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0735026-A1 | Method for the production of isoquinoline derivatives and their use as intermediates in the preparation of indole derivatives | TORAY INDUSTRIES, INC. (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5539119-A | MULTISTAGE FORMATION BY OXIDATION, REDUCING A CARBAMATE TO FORM AN ENAMINE, FORMING AN OXIDE | TORAY INDUSTRIES, INC. (JP) | 1996-07-23 | — | — | US | disclosed |
| US-5244904-A | Immunorepressant, analgesic | TORAY INDUSTRIES, INC. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0485636-A1 | INDOLE DERIVATIVE | TORAY INDUSTRIES, INC. (JP) | 1992-05-20 | — | — | EP | disclosed |