Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395140 | 1.00 | OPRM1 (0.57) | OPRM1OPRD1OPRK1ALDH1A1MEN1 | |
| SCHEMBL8792218 | 0.88 | OPRM1 (0.56) | OPRM1OPRD1OPRK1ALDH1A1CXCR3 | |
| SCHEMBL11243848 | 0.81 | OPRM1 (0.49) | OPRM1OPRD1OPRK1ALDH1A1MEN1 | |
| SCHEMBL16385999 | 0.79 | OPRL1 (0.53) | OPRM1ALDH1A1MEN1LMNAMAPT | |
| SCHEMBL17815774 | 0.79 | OPRL1 (0.53) | OPRM1ALDH1A1MEN1LMNAMAPT | |
| SCHEMBL8793354 | 0.78 | OPRM1 (0.55) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11547501 | 0.76 | CYP1A2 (0.51) | ALDH1A1CXCR3CHRM3CHRM2OPRL1 | |
| Iodide SCHEMBL11547732 | 0.74 | CYP1A2 (0.50) | ALDH1A1CXCR3CHRM3CHRM2OPRL1 | |
| SCHEMBL8393176 | 0.74 | SIGMAR1 (0.43) | OPRM1ALDH1A1MEN1LMNAMAPT | |
| SCHEMBL7486456 | 0.74 | OPRM1 (0.60) | OPRM1OPRD1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939551-A | Process for producing 4a-aryldecahydroisoquinoline derivatives | TORAY INDUSTRIES, INC. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0845460-A1 | PROCESS FOR PRODUCING 4a-ARYLDECAHYDROISOQUINOLINE DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1998-06-03 | — | — | EP | disclosed |