Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP14 | P50281 | 2/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486316 | 0.86 | PPARA (0.52) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL27508683 | 0.82 | MEN1 (0.53) | MEN1KMT2AGAARAB9AALDH1A1 | |
| SCHEMBL8488202 | 0.80 | GAA (0.56) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL18477948 | 0.78 | MAOB (0.73) | L3MBTL1MEN1KMT2AGAARAB9A | |
| SCHEMBL10461025 | 0.78 | ALDH1A1 (0.57) | L3MBTL1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL27508684 | 0.78 | MEN1 (0.53) | MEN1KMT2AGAARAB9AALDH1A1 | |
| SCHEMBL13956882 | 0.76 | CA1 (0.57) | MEN1KMT2AGAAALDH1A1HTT | |
| SCHEMBL8795501 | 0.75 | KDM4E (0.53) | L3MBTL1MEN1KMT2AGAARAB9A | |
| SCHEMBL9780583 | 0.75 | ALDH1A1 (0.67) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL18868405 | 0.75 | L3MBTL1 (1.00) | L3MBTL1GAARAB9AALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |