Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794869 | 0.80 | L3MBTL1 (0.56) | GAAKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL9780583 | 0.79 | ALDH1A1 (0.67) | GAAKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL8488199 | 0.78 | GAA (0.52) | GAAKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL8486316 | 0.78 | PPARA (0.52) | GAAKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL27508683 | 0.77 | MEN1 (0.53) | GAAKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL27508684 | 0.77 | MEN1 (0.53) | GAAKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL8487175 | 0.76 | MEN1 (0.49) | GAAKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL10453046 | 0.76 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1SIGMAR1TDP1 | |
| SCHEMBL1876555 | 0.75 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1PKMHTT | |
| SCHEMBL1148367 | 0.75 | GAA (0.60) | GAAKMT2AMEN1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877196-A | N- 4-(imidazolyl or pyrazolyl)phenyl(oxy, sulfinyl, sulfenyl or sulfonyl)alkyl!carboxamides, sulfonamides or phosphoramides having antiarrhythmic properties | AMERICAN CYANAMID COMPANY (US) | 1999-03-02 | — | — | US | disclosed |