Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP14 | P50281 | 2/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508684 | 0.84 | MEN1 (0.53) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL8794869 | 0.82 | L3MBTL1 (0.56) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL8486316 | 0.78 | PPARA (0.52) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL8488202 | 0.77 | GAA (0.56) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL9510762 | 0.75 | GRIA4 (0.46) | MEN1KMT2AGAAALDH1A1CA12 | |
| SCHEMBL9780583 | 0.72 | ALDH1A1 (0.67) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL9512047 | 0.72 | IDO1 (0.60) | ALDH1A1KDM4EMMP2MMP14ADAMTS4 | |
| SCHEMBL8487175 | 0.72 | MEN1 (0.49) | MEN1KMT2AGAAALDH1A1MMP2 | |
| SCHEMBL6323398 | 0.71 | ADAMTS4 (0.61) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL27513379 | 0.71 | GPR88 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1162596-A | Antiarrhythmic Agents | AMERICAN CYANAMID CO (US) | 1997-10-22 | — | — | CN | claimed |