Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488376 | 0.88 | NPC1 (0.62) | NPC1RAB9AALDH1A1HPGDADRB2 | |
| SCHEMBL16556594 | 0.78 | KDM4E (0.63) | ALDH1A1HPGDSMN1; SMN2EPHX2NR1H4 | |
| SCHEMBL10495144 | 0.77 | NPC1 (0.65) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL10495115 | 0.77 | NPC1 (0.64) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL22859084 | 0.76 | ALDH1A1 (0.83) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL3555970 | 0.75 | NPC1 (0.61) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL9733253 | 0.75 | NPC1 (0.69) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13508331 | 0.75 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2EPHX2NR1H4KMT2A | |
| SCHEMBL748841 | 0.74 | SMN1; SMN2 (0.64) | ALDH1A1HPGDSMN1; SMN2EPHX2NR1H4 | |
| SCHEMBL9389817 | 0.73 | NPC1 (0.67) | NPC1RAB9AALDH1A1HPGDADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | claimed |
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |