Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794265 | 0.86 | ABCC9 (0.34) | ABCB1KCNE1KCNQ1ABCC9PDE4A | |
| SCHEMBL8794643 | 0.86 | ABCC9 (0.39) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL10381385 | 0.83 | ABCB1 (0.35) | ABCB1ABCC9PDE4APDE4BPDE4C | |
| SCHEMBL8795403 | 0.78 | ABCB1 (0.34) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL10381365 | 0.77 | ABCC9 (0.41) | ABCB1ABCC9PDE4APDE4BPDE4C | |
| SCHEMBL10381384 | 0.72 | RARA (0.42) | ABCB1MEN1KMT2AABCC9 | |
| SCHEMBL9523959 | 0.69 | PDE4A (0.37) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL9550599 | 0.69 | KDM4E (0.43) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL9394910 | 0.69 | KCNE1 (0.35) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL9194763 | 0.69 | KCNE1 (0.35) | ABCB1KCNE1KCNQ1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |