Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795746 | 0.86 | ABCC9 (0.39) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL8794265 | 0.85 | ABCC9 (0.34) | ABCB1KCNE1KCNQ1ABCC9KDM4E | |
| SCHEMBL8795137 | 0.78 | SMN1; SMN2 (0.38) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL8794704 | 0.76 | ABCB1 (0.33) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL10381385 | 0.73 | ABCB1 (0.35) | ABCB1ABCC9KDM4E | |
| SCHEMBL8795668 | 0.72 | ABCC9 (0.34) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL10381365 | 0.71 | ABCC9 (0.41) | ABCB1ABCC9KDM4E | |
| SCHEMBL8794643 | 0.68 | ABCC9 (0.39) | ABCB1KCNE1KCNQ1MEN1CYP1A2 | |
| SCHEMBL9527675 | 0.68 | METAP2 (0.37) | KDM4E | |
| SCHEMBL8314385 | 0.67 | ABCC9 (0.36) | ABCB1KCNE1KCNQ1ABCC9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541807-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-12-17 | — | — | EP | disclosed |
| EP-0766669-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035283-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| US-5412117-A | Potassium channel activators, antiasmatics, antiepileptics | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0541807-A1 | NOVEL BENZOPYRAN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-05-19 | — | — | EP | disclosed |