Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.44 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525002 | 0.82 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9376910 | 0.80 | ESPL1 (0.37) | ESPL1ALDH1A1LMNA | |
| SCHEMBL8796317 | 0.80 | ABCC9 (0.42) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9525790 | 0.79 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9527732 | 0.78 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8335425 | 0.78 | ABCC9 (0.43) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8795248 | 0.77 | PTGS2 (0.35) | ESPL1ALDH1A1LMNA | |
| SCHEMBL9527906 | 0.77 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 | |
| SCHEMBL6369348 | 0.76 | ABCC9 (0.62) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8794831 | 0.76 | ESPL1 (0.37) | ESPL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586405-B1 | NOVEL 2H-BENZO[b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS | BEIERSDORF LILLY GMBH (DE) | 1997-09-10 | — | — | EP | claimed |