Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535545 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDKDM4ETDP1 | |
| SCHEMBL9378364 | 0.69 | LMNA (0.34) | MAPT | |
| SCHEMBL17414489 | 0.69 | ATM (0.34) | ALDH1A1MAPTHPGDRAD52OPRD1 | |
| SCHEMBL14162088 | 0.66 | CHRM1 (0.35) | ALDH1A1MAPTHPGDRAD52 | |
| SCHEMBL7738968 | 0.66 | ALDH1A1 (0.35) | ALDH1A1MAPTHPGDKDM4ETDP1 | |
| SCHEMBL9845357 | 0.65 | OPRD1 (0.45) | ALDH1A1MAPTHPGDKDM4ETDP1 | |
| SCHEMBL10652225 | 0.65 | ALDH1A1 (0.32) | ALDH1A1MAPTHPGDOPRD1KCNH2 | |
| SCHEMBL6859852 | 0.62 | ALDH1A1 (0.34) | ALDH1A1MAPTHPGDOPRD1OPRK1 | |
| SCHEMBL17746831 | 0.62 | LPL (0.39) | ALDH1A1MAPTHPGD | |
| SCHEMBL8795163 | 0.61 | MEN1 (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586405-B1 | NOVEL 2H-BENZO[b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS | BEIERSDORF LILLY GMBH (DE) | 1997-09-10 | — | — | EP | disclosed |
| EP-0586405-A1 | NOVEL 2H-BENZO b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS. | BEIERSDORF LILLY GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020671-A1 | NOVEL 2H-BENZO[b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS | BEIERSDORF-LILLY GMBH (DE) | 1992-11-26 | — | — | WO | disclosed |