SCHEMBL879528

SCHEMBL879528

CC(C)C1(OC(=O)NCc2ccccc2)CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.45
EPHX1 P07099 1/20 0.45
HPGD P15428 1/20 0.45
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
PTPN1 P18031 1/20 0.43
BCHE P06276 1/20 0.42
SLC1A2 P43004 1/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8737829 0.87 CYP3A4 (0.47) EPHX1KMT2AMEN1NPC1RAB9A
SCHEMBL28032464 0.75 CTSK (0.53) EPHX1HPGDBCHE
SCHEMBL3898239 0.74 CTSL (0.57) EPHX1HPGDSMN1; SMN2
SCHEMBL27935589 0.73 GAA (0.47) ATMEPHX1HPGDKMT2AALDH1A1
SCHEMBL6400043 0.72 TSHR (0.42) L3MBTL1ALDH1A1KDM4E
SCHEMBL25518194 0.72 KMT2A (0.53) MAPTL3MBTL1KMT2AALDH1A1MEN1
SCHEMBL7182602 0.72 MAPT (0.43) MAPTL3MBTL1ATMHPGDKMT2A
SCHEMBL3898232 0.72 CTSB (0.43) ATMEPHX1HPGDSMN1; SMN2BCHE
SCHEMBL12111459 0.71 NPC1 (0.57) MAPTL3MBTL1KMT2AALDH1A1MEN1
SCHEMBL28997665 0.71 MC4R (0.46) MAPTL3MBTL1ATMALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2434343-A1 Resist composition, resist film therefrom and method of forming pattern therewith Fujifilm Corporation (JP) 2012-03-28 EP disclosed