Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482651 | 0.89 | CYP2D6 (0.54) | CYP2D6MEN1KMT2AALDH1A1PKM | |
| SCHEMBL8487175 | 0.81 | MEN1 (0.49) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL8794686 | 0.75 | CYP2D6 (0.53) | CYP2D6MEN1KMT2AGAA | |
| SCHEMBL8488202 | 0.75 | GAA (0.56) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL8795018 | 0.74 | CYP2D6 (0.52) | CYP2D6MEN1KMT2AGAA | |
| SCHEMBL8794869 | 0.74 | L3MBTL1 (0.56) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL8486316 | 0.72 | PPARA (0.52) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL27508684 | 0.71 | MEN1 (0.53) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL27508683 | 0.71 | MEN1 (0.53) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL8795501 | 0.71 | KDM4E (0.53) | MEN1KMT2AGAAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0634401-B1 | MDR reversal agents | AMERICAN CYANAMID CO (US) | 1997-08-13 | — | — | EP | disclosed |
| US-5561141-A | POTENTIATE ACTIVITY OF ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0634401-A1 | MDR reversal agents | AMERICAN CYANAMID COMPANY (US) | 1995-01-18 | — | — | EP | disclosed |