Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27987188 | 0.79 | TAAR1 (0.45) | MAOBLOXL2TAAR1PLAUPLG | |
| SCHEMBL28121075 | 0.79 | TAAR1 (0.45) | MAOBLOXL2TAAR1PLAUPLG | |
| SCHEMBL756850 | 0.76 | DHFR (0.51) | ACHEMAOBLOXL2TAAR1PNMT | |
| SCHEMBL11289700 | 0.74 | MAOA (0.44) | MAOB | |
| SCHEMBL26920830 | 0.74 | MAOB (0.40) | ACHEMAOBLOXL2TAAR1PLAU | |
| SCHEMBL297093 | 0.73 | MEP1B (0.50) | MAOBLOXL2TAAR1PNMTENPP2 | |
| SCHEMBL29793524 | 0.73 | MEP1B (0.50) | MAOBLOXL2TAAR1PNMTENPP2 | |
| Hydrochloric Acid SCHEMBL25370222 | 0.71 | MEP1B (0.49) | MAOBLOXL2TAAR1PNMTENPP2 | |
| Hydrochloric Acid SCHEMBL30580212 | 0.71 | MEP1B (0.49) | MAOBLOXL2TAAR1PNMTENPP2 | |
| SCHEMBL24003314 | 0.71 | TAAR1 (0.44) | MAOBLOXL2TAAR1PLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758653-A1 | IMIDAZOQUINAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |