Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796050 | 0.79 | CYP3A4 (0.35) | SCN9A | |
| SCHEMBL9334077 | 0.77 | NPY1R (0.32) | — | |
| SCHEMBL8796347 | 0.75 | RARA (0.31) | — | |
| SCHEMBL16516779 | 0.70 | CYP3A4 (0.37) | — | |
| SCHEMBL1421446 | 0.69 | DRD2 (0.39) | — | |
| SCHEMBL3954770 | 0.67 | PREP (0.35) | — | |
| SCHEMBL8795608 | 0.67 | SCN9A (0.36) | SCN9A | |
| SCHEMBL19354829 | 0.66 | SLC6A4 (0.36) | — | |
| SCHEMBL275754 | 0.66 | ERN1 (0.39) | — | |
| SCHEMBL8796193 | 0.64 | CXCR3 (0.36) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629604-B1 | Alicyclic phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5436369-A | Alicyclic phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0629604-A2 | Alicyclic phospholipase A2 inhibitors | Bristol-Myers Company (US) | 1994-12-21 | — | — | EP | disclosed |