Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796569 | 1.00 | PTPN11 (0.37) | PTPN11PLA2G4ASMPD1LTB4RHDAC3 | |
| SCHEMBL8796294 | 0.99 | PTPN11 (0.36) | PTPN11PLA2G4ASMPD1LTB4RHDAC3 | |
| SCHEMBL8796289 | 0.99 | PTPN11 (0.36) | PTPN11PLA2G4ASMPD1LTB4RHDAC3 | |
| SCHEMBL8795838 | 0.89 | PLA2G4A (0.46) | PLA2G4ASMPD1SMN1; SMN2 | |
| SCHEMBL8795848 | 0.89 | PLA2G4A (0.46) | PLA2G4ASMPD1SMN1; SMN2 | |
| SCHEMBL8795820 | 0.87 | NPC1 (0.39) | PTPN11PLA2G4ALTB4RSMN1; SMN2HPGD | |
| SCHEMBL8795809 | 0.87 | NPC1 (0.39) | PTPN11PLA2G4ALTB4RSMN1; SMN2HPGD | |
| SCHEMBL8796557 | 0.86 | SMPD1 (0.37) | PTPN11PLA2G4ASMPD1LTB4RSMN1; SMN2 | |
| SCHEMBL8796548 | 0.86 | SMPD1 (0.37) | PTPN11PLA2G4ASMPD1LTB4RSMN1; SMN2 | |
| SCHEMBL8796723 | 0.83 | PTPN11 (0.43) | PTPN11PLA2G4ASMPD1LTB4RHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629604-B1 | Alicyclic phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5436369-A | Alicyclic phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0629604-A2 | Alicyclic phospholipase A2 inhibitors | Bristol-Myers Company (US) | 1994-12-21 | — | — | EP | disclosed |