Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.55 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990759 | 0.89 | AVPR1A (0.68) | AVPR1AAVPR2AVPR1BKMT2A | |
| SCHEMBL6995228 | 0.86 | AVPR2 (0.51) | AVPR1AAVPR2AVPR1BNPC1RAB9A | |
| SCHEMBL6991988 | 0.86 | AVPR1A (0.56) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL6996850 | 0.84 | LMNA (0.51) | AVPR1AAVPR2AVPR1BKMT2A | |
| SCHEMBL6987523 | 0.84 | AVPR2 (0.56) | AVPR1AAVPR2AVPR1BNPC1RAB9A | |
| SCHEMBL6985550 | 0.83 | AVPR2 (0.47) | AVPR1AAVPR2AVPR1BALDH1A1KMT2A | |
| SCHEMBL8796709 | 0.77 | AVPR1A (0.70) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL6988983 | 0.76 | AVPR1A (0.79) | AVPR1AAVPR2AVPR1BKMT2A | |
| SCHEMBL6987427 | 0.73 | AVPR1A (0.59) | AVPR1AAVPR2AVPR1BNPC1RAB9A | |
| SCHEMBL6995599 | 0.72 | AVPR1A (0.56) | AVPR1AAVPR2AVPR1BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |