Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.42 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797141 | 0.95 | L3MBTL1 (0.49) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8797106 | 0.94 | LMNA (0.49) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8797114 | 0.93 | LMNA (0.51) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8797462 | 0.93 | LMNA (0.51) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8797103 | 0.93 | LMNA (0.51) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8796913 | 0.90 | CHRNA7 (0.52) | ALDH1A1HSD17B10CHRNA7FKBP1A | |
| SCHEMBL8797402 | 0.87 | CHRNA7 (0.53) | CHRNA7FKBP1A | |
| SCHEMBL8797472 | 0.86 | CHRNA7 (0.47) | ALDH1A1HPGDHSD17B10CHRNA7L3MBTL1 | |
| SCHEMBL8797096 | 0.86 | CHRNA7 (0.47) | ALDH1A1HPGDHSD17B10CHRNA7L3MBTL1 | |
| SCHEMBL8797271 | 0.84 | CHRNA7 (0.47) | LMNACHRNA7L3MBTL1TDP1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801065-A1 | 1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1997-10-15 | — | — | EP | disclosed |