Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797103 | 1.00 | LMNA (0.51) | LMNAL3MBTL1TDP1CHRNA7MAPT | |
| SCHEMBL8797114 | 1.00 | LMNA (0.51) | LMNAL3MBTL1TDP1CHRNA7MAPT | |
| SCHEMBL8797106 | 0.99 | LMNA (0.49) | LMNAL3MBTL1TDP1CHRNA7MAPT | |
| SCHEMBL8797141 | 0.96 | L3MBTL1 (0.49) | LMNAL3MBTL1TDP1CHRNA7ALDH1A1 | |
| SCHEMBL8797176 | 0.93 | LMNA (0.52) | LMNAL3MBTL1TDP1CHRNA7ALDH1A1 | |
| SCHEMBL8796913 | 0.88 | CHRNA7 (0.52) | CHRNA7ALDH1A1HSD17B10 | |
| SCHEMBL8797402 | 0.84 | CHRNA7 (0.53) | CHRNA7 | |
| SCHEMBL8797472 | 0.83 | CHRNA7 (0.47) | L3MBTL1CHRNA7ALDH1A1HPGDMEN1 | |
| SCHEMBL8797096 | 0.83 | CHRNA7 (0.47) | L3MBTL1CHRNA7ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8797927 | 0.83 | KMT2A (0.47) | LMNAL3MBTL1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801065-A1 | 1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1997-10-15 | — | — | EP | disclosed |