Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452304 | 0.78 | SPHK1 (0.37) | PPARAPPARGS1PR4S1PR1S1PR5 | |
| SCHEMBL14337540 | 0.77 | ACHE (0.38) | PPARAPPARGCA1CA2 | |
| SCHEMBL7295581 | 0.74 | POLB (0.52) | — | |
| SCHEMBL3227309 | 0.74 | SLC6A4 (0.41) | PPARAPPARGAOC3SLC6A4 | |
| SCHEMBL20739983 | 0.74 | ACACB (0.47) | THRBPPARAPPARG | |
| SCHEMBL9641445 | 0.69 | LMNA (0.59) | CA1CA2 | |
| SCHEMBL3028156 | 0.69 | LMNA (0.53) | — | |
| SCHEMBL1610768 | 0.69 | LPL (0.50) | THRBTAAR1SLC6A4CA2 | |
| SCHEMBL1610396 | 0.69 | NQO1 (0.61) | — | |
| Acetic Acid SCHEMBL7350375 | 0.68 | PPARG (0.45) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | claimed |
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | claimed |