Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797285 | 0.78 | THRB (0.35) | CA2PPARAPPARGS1PR4S1PR1 | |
| Hydrochloric Acid SCHEMBL29796884 | 0.72 | SLC2A1 (0.46) | SPHK1PPARAS1PR4S1PR1S1PR5 | |
| SCHEMBL8798288 | 0.71 | LTA4H (0.50) | LTA4HEPHX2MEN1USP2ALDH1A1 | |
| SCHEMBL9112221 | 0.68 | POLB (0.50) | CA2LTA4HEPHX2PPARACYP4F2 | |
| SCHEMBL9027085 | 0.68 | POLB (0.50) | CA2LTA4HEPHX2PPARACYP4F2 | |
| SCHEMBL8723163 | 0.67 | ALDH1A1 (0.51) | SPHK1PPARAS1PR4S1PR1S1PR5 | |
| SCHEMBL9846533 | 0.67 | S1PR1 (0.39) | SPHK1S1PR4S1PR1S1PR5S1PR2 | |
| SCHEMBL7295581 | 0.67 | POLB (0.52) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL23266258 | 0.66 | POLB (0.51) | CA2LTA4HEPHX2PPARACYP4F2 | |
| SCHEMBL8797551 | 0.65 | ALDH1A1 (0.52) | LTA4HEPHX2MEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552379-A1 | DIHYDROPYRIDINE DERIVATIVES, AND PROCESS FOR THEIR PREPARATION. | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-07-28 | — | — | EP | disclosed |