Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797462 | 0.83 | LMNA (0.51) | KMT2ALMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8797114 | 0.83 | LMNA (0.51) | KMT2ALMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8797103 | 0.83 | LMNA (0.51) | KMT2ALMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8797106 | 0.82 | LMNA (0.49) | KMT2ALMNAGAAMAPTKDM4E | |
| SCHEMBL8655419 | 0.80 | KDM4E (0.42) | GAAPKMMAPTKDM4EALDH1A1 | |
| SCHEMBL8797141 | 0.79 | L3MBTL1 (0.49) | LMNAGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8797176 | 0.76 | LMNA (0.52) | LMNAGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8796913 | 0.71 | CHRNA7 (0.52) | ALDH1A1 | |
| SCHEMBL8656020 | 0.71 | HSD17B10 (0.45) | KMT2ALMNAMAPTALDH1A1DRD2 | |
| SCHEMBL8797402 | 0.68 | CHRNA7 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801065-A1 | 1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1997-10-15 | — | — | EP | disclosed |