Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.54 |
| ▸ | CCKAR | P32238 | 9/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | NOTCH1 | P46531 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | NOTCH3 | Q9UM47 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752996 | 0.79 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL8783598 | 0.79 | ACE (0.44) | CCKBR | |
| SCHEMBL8795891 | 0.75 | GABRP (0.55) | CCKBRCCKARNOTCH1PSEN1PSEN2 | |
| SCHEMBL9423149 | 0.74 | CCKBR (0.75) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL8089998 | 0.73 | F10 (0.44) | — | |
| SCHEMBL8095747 | 0.73 | F10 (0.44) | — | |
| SCHEMBL8095859 | 0.73 | F10 (0.44) | — | |
| SCHEMBL7752708 | 0.72 | CCKBR (0.46) | CCKBRCCKAR | |
| SCHEMBL8089888 | 0.72 | F10 (0.41) | CCKBRCCKAR | |
| SCHEMBL7306632 | 0.71 | CCKBR (0.60) | CCKBRCCKARADRB2TSPOGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755394-A1 | A METHOD OF INDUCING CHOLECYSTOKININ AGONIST ACTIVITY USING 1,4-BENZODIAZEPINE COMPOUNDS | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028399-A1 | A METHOD OF INDUCING CHOLECYSTOKININ AGONIST ACTIVITY USING 1,4-BENZODIAZEPINE COMPOUNDS | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | disclosed |