Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | HTR2A | P28223 | 6/20 | 0.54 |
| ▸ | HTR7 | P34969 | 5/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.51 |
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798171 | 0.85 | DRD2 (0.52) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL8797552 | 0.84 | DRD2 (0.58) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL8797479 | 0.83 | DRD2 (0.56) | DRD2HTR2AHTR7HTR1AADRA1A | |
| SCHEMBL8797503 | 0.81 | DRD2 (0.61) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL8797827 | 0.81 | DRD2 (0.49) | DRD2HTR2AHTR7HTR1AADRA1A | |
| SCHEMBL8797848 | 0.78 | HTR7 (0.53) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL13875120 | 0.78 | SIGMAR1 (0.69) | DRD2HTR7HTR1ADRD3 | |
| SCHEMBL13532761 | 0.76 | DRD2 (0.61) | DRD2HTR2AHTR7HTR1AADRA1A | |
| Hydrochloric Acid SCHEMBL11642305 | 0.75 | SIGMAR1 (0.60) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL13875122 | 0.75 | SIGMAR1 (0.71) | DRD2HTR7HTR1AADRA1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707571-B1 | 3,5-DIOXO-(2H,4H)-1,2,4-TRIAZINE DERIVATIVES AS 5HT1A LIGANDS | PF MEDICAMENT (FR) | 1997-05-02 | — | — | EP | claimed |
| US-5591743-A | ANXIOLYTIC DRUGS OR HYPOTENSIVE AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1997-01-07 | — | — | US | claimed |