Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 6/20 | 0.37 |
| ▸ | CDC25B | P30305 | 6/20 | 0.37 |
| ▸ | CDC25C | P30307 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45540 | 0.98 | SORT1 (0.58) | SORT1ACHEBACE1SCDCDC25A | |
| SCHEMBL11963993 | 0.92 | SORT1 (0.59) | SORT1CYP1A2ALDH1A1GAAMAPT | |
| SCHEMBL15222747 | 0.72 | SORT1 (0.58) | SORT1 | |
| SCHEMBL11022532 | 0.69 | SORT1 (0.55) | SORT1CDC25ACDC25BCDC25CALDH1A1 | |
| SCHEMBL449761 | 0.68 | ACHE (0.38) | ACHEBACE1SCDCDC25ACDC25B | |
| SCHEMBL11685919 | 0.67 | DHFR (0.50) | ACHEBACE1CDC25ACDC25BCDC25C | |
| SCHEMBL9662341 | 0.65 | ACHE (0.35) | ACHEBACE1SCDALDH1A1THRB | |
| SCHEMBL452497 | 0.65 | ACHE (0.35) | ACHEBACE1SCDCDC25ACDC25B | |
| SCHEMBL12356587 | 0.65 | TSHR (0.40) | ACHEBACE1SCDALDH1A1THRB | |
| SCHEMBL13280457 | 0.65 | SCD (0.45) | ACHEBACE1SCDCDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532725-B1 | ISOXAZOLE DERIVATIVES AS LIGHT SCREENING AGENT | GIVAUDAN ROURE INT (CH) | 1997-01-29 | — | — | EP | disclosed |
| US-5536453-A | COSMETICS | GIVAUDAN-ROURE CORPORATION, (US) | 1996-07-16 | — | — | US | disclosed |
| US-5481001-A | RADIATION RESISTANT COMPOSITIONS FOR COSMETICS | GIVAUDAN-ROURE CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0532725-A1 | LIGHT SCREENING AGENT. | GIVAUDAN ROURE INT (CH) | 1993-03-24 | — | — | EP | disclosed |
| WO-1992017461-A1 | LIGHT SCREENING AGENT | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1992-10-15 | — | — | WO | disclosed |