Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443036 | 0.88 | KMO (0.47) | HSD17B10ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL21749975 | 0.72 | MAPT (0.39) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL23201168 | 0.72 | ALDH1A1 (0.51) | HSD17B10ALDH1A1KMT2AMAPTMAPK14 | |
| SCHEMBL25586500 | 0.69 | HSD17B10 (0.47) | HSD17B10MAPK14ADORA2A | |
| SCHEMBL11821346 | 0.69 | KMO (0.51) | HSD17B10ALDH1A1KMT2AMAPTKMO | |
| SCHEMBL28493467 | 0.69 | KDM4E (0.60) | MAPK14KMOKDM4ESYKJMJD6 | |
| SCHEMBL3515932 | 0.68 | BDKRB1 (0.42) | HSD17B10ALDH1A1MAPTTOP2ABDKRB1 | |
| SCHEMBL30285097 | 0.67 | SLC6A3 (0.63) | HSD17B10ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL3516370 | 0.67 | GABRG2 (0.39) | HSD17B10ALDH1A1MAPTBDKRB1KDM4E | |
| SCHEMBL13521521 | 0.67 | CCNT1 (0.61) | HSD17B10ALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804438-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-11-05 | — | — | EP | disclosed |