Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | FNTB | P49356 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657182 | 1.00 | PRKCZ (0.48) | PRKCZFNTAFNTBFFAR1GABBR2 | |
| SCHEMBL1532918 | 0.90 | PRKCZ (0.54) | PRKCZFNTAFNTBFFAR1GABBR2 | |
| SCHEMBL12268167 | 0.88 | FNTA (0.47) | PRKCZFNTAFNTBFFAR1LMNA | |
| SCHEMBL657179 | 0.87 | FFAR1 (0.47) | PRKCZFNTAFNTBFFAR1GABBR2 | |
| SCHEMBL7728006 | 0.85 | FFAR1 (0.50) | PRKCZFNTAFNTBFFAR1TSHR | |
| SCHEMBL657117 | 0.83 | PRKCZ (0.53) | PRKCZGABBR2GABBR1LMNACYP2C9 | |
| SCHEMBL7811403 | 0.82 | TACR1 (0.46) | FNTAFNTBLMNACYP2C9CYP3A4 | |
| SCHEMBL7873209 | 0.82 | FNTA (0.46) | PRKCZFNTAFNTBFFAR1ALDH1A1 | |
| SCHEMBL657723 | 0.82 | GABBR2 (0.65) | PRKCZFNTAFNTBFFAR1GABBR2 | |
| SCHEMBL7633288 | 0.81 | GABBR2 (0.68) | PRKCZFFAR1GABBR2GABBR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773929-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996039386-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |