Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7728008 | 0.94 | SLC6A3 (0.49) | FFAR1SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL12268167 | 0.86 | FNTA (0.47) | FFAR1SLC6A3PRKCZCYP26A1FNTA | |
| SCHEMBL8798403 | 0.85 | PRKCZ (0.48) | FFAR1PRKCZCYP26A1FNTAFNTB | |
| SCHEMBL657182 | 0.85 | PRKCZ (0.48) | FFAR1PRKCZCYP26A1FNTAFNTB | |
| SCHEMBL1532918 | 0.85 | PRKCZ (0.54) | FFAR1PRKCZCYP26A1FNTAFNTB | |
| SCHEMBL7873751 | 0.85 | F10 (0.45) | FFAR1SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL393911 | 0.84 | GABBR2 (0.58) | FFAR1PRKCZFNTAFNTBTSHR | |
| SCHEMBL7871985 | 0.84 | SLC6A3 (0.44) | FFAR1SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL7873209 | 0.83 | FNTA (0.46) | FFAR1SLC6A2SLC6A4SLC6A3PRKCZ | |
| SCHEMBL8771122 | 0.82 | SLC6A3 (0.49) | FFAR1SLC6A2SLC6A4SLC6A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410306-B1 | PREPARING PREFERENTIAL ENANTIMORPHS; OBTAIN CHEMICAL INTERMEDIATE, INCUBATE WITH ENZYMES, RECOVER PREFERENTIAL ENANTIMORPHS | SCHERING CORPORATION | 2002-06-25 | — | — | US | disclosed |
| EP-0808303-B1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000050628-A1 | ENANTIOSELECTIVE ENZYMATIC HYDROLYSIS OF 3-SUBSTITUTED ESTERS OF GLUTARIC ACID | SCHERING CORPORATION (US) | 2000-08-31 | — | — | WO | disclosed |
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |