Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858099 | 0.83 | KMT2A (0.62) | ALDH1A1KMT2AL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL5856811 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL8798404 | 0.79 | PRKCZ (0.40) | ALDH1A1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL5847436 | 0.76 | KMT2A (0.55) | ALDH1A1KMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL8798443 | 0.75 | KMT2A (0.57) | ALDH1A1KMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL6219736 | 0.75 | KMT2A (0.54) | ALDH1A1KMT2AMEN1HPGDL3MBTL1 | |
| SCHEMBL7815155 | 0.75 | KMT2A (0.57) | ALDH1A1KMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL5847398 | 0.75 | KMT2A (0.54) | ALDH1A1KMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL20379845 | 0.74 | PTGS1 (0.59) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL20380123 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1085661-C | Piperidine derivatives as neurokinin antagonists | SCHERING CORP (US) | 2002-05-29 | — | — | CN | disclosed |
| CN-1161033-A | Piperidine derivatives as neurokinin antagonists | SCHERING CORP (US) | 1997-10-01 | — | — | CN | disclosed |
| EP-0773929-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996039386-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |