Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811407 | 0.86 | FNTA (0.38) | FNTAFNTBHSD17B2LMNAALDH1A1 | |
| SCHEMBL8799604 | 0.83 | FNTA (0.42) | FNTAFNTBLMNAALDH1A1CYP3A4 | |
| SCHEMBL657183 | 0.80 | SLC6A2 (0.44) | CYP2D6THRBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8798451 | 0.79 | ALDH1A1 (0.46) | HSD17B2CYP2C9ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL1532918 | 0.79 | PRKCZ (0.54) | PRKCZCYP26A1FNTAFNTBGABBR2 | |
| SCHEMBL7815285 | 0.79 | LMNA (0.37) | LMNAALDH1A1FFAR1 | |
| SCHEMBL657182 | 0.71 | PRKCZ (0.48) | PRKCZCYP26A1FNTAFNTBGABBR2 | |
| SCHEMBL8798403 | 0.71 | PRKCZ (0.48) | PRKCZCYP26A1FNTAFNTBGABBR2 | |
| SCHEMBL7633288 | 0.70 | GABBR2 (0.68) | PRKCZGABBR2GABBR1LMNACYP2C9 | |
| Hydrochloric Acid SCHEMBL560490 | 0.69 | GABBR2 (0.66) | PRKCZGABBR2GABBR1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773929-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996039386-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |