SCHEMBL8798554

SCHEMBL8798554

CCOC(=O)CCCCCN(N)C(=O)Nc1cc(OC)cc(C(C)(C)C)c1OCOC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
VCAM1 P19320 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8798530 0.87 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL8798368 0.86 SMN1; SMN2 (0.39) SMN1; SMN2
SCHEMBL8798986 0.81 MAPT (0.32)
SCHEMBL8702761 0.72 LPAR1 (0.39) SMN1; SMN2VCAM1
SCHEMBL8804341 0.72 LMNA (0.34)
SCHEMBL8797685 0.71 HDAC1 (0.34) VCAM1
SCHEMBL8801653 0.69 LPAR1 (0.34)
SCHEMBL8798826 0.68 MAPT (0.37) SMN1; SMN2
SCHEMBL8703601 0.67 MAPK14 (0.47) SMN1; SMN2
SCHEMBL8798797 0.66 NPC1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790240-A1 Phenol-derivatives having pharmaceutical activity and process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1997-08-20 EP disclosed
EP-0781285-A1 FUSED INDOLE AND QUINOXALINE DERIVATIVES, THEIR PREPARATION AND USE NEUROSEARCH A/S (DK) 1997-07-02 EP disclosed