Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281995 | 0.87 | NPC1 (0.39) | NPC1RAB9AMMP3ACHEPPARA | |
| Hydrochloric Acid SCHEMBL6245752 | 0.86 | NPC1 (0.39) | NPC1RAB9AMMP3ACHEPPARA | |
| SCHEMBL8799426 | 0.79 | ACHE (0.42) | NPC1RAB9AMMP3ACHEPPARA | |
| SCHEMBL3740322 | 0.78 | RAB9A (0.38) | NPC1RAB9AMMP3ACHEPPARA | |
| SCHEMBL8799725 | 0.78 | ACHE (0.37) | NPC1RAB9AACHEPPARATDP1 | |
| Hydrochloric Acid SCHEMBL8798679 | 0.78 | HRH3 (0.33) | RAB9AALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL8797685 | 0.77 | HDAC1 (0.34) | PPARAALDH1A1PPARGPPARDHDAC1 | |
| SCHEMBL8804341 | 0.74 | LMNA (0.34) | NPC1PPARATDP1PPARGPPARD | |
| SCHEMBL8797836 | 0.73 | CTSS (0.38) | ACHEPPARAPPARGPPARDMEN1 | |
| Hydrochloric Acid SCHEMBL8798772 | 0.73 | TSHR (0.35) | NPC1RAB9AALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790240-A1 | Phenol-derivatives having pharmaceutical activity and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |